Jiachen Wen

Synthesis and biological evaluation of quinoline derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors

Kun Li, Ying Li, Di Zhou et al. · Bioorganic & Medicinal Chemistry · 2016 · 68 citations · Full text

Medicine, Medicinal Chemistry, Oncology +11

Identification of N-(6-mercaptohexyl)-3-(4-pyridyl)-1H-pyrazole-5-carboxamide and its disulfide prodrug as potent histone deacetylase inhibitors with in vitro and in vivo anti-tumor efficacy

Jiachen Wen, Yu Bao, Qun Niu et al. · European Journal of Medicinal Chemistry · 2016 · 49 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Induction of ferroptosis: A new strategy for the control of bacterial infections

Rongxian Guo, Xin Fang, Ke Shang et al. · Microbiological Research · 2024 · 31 citations

Life Sciences, Infectious Diseases, Microbiology +12

Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1H-pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR study

Jiachen Wen, Qun Niu, Jiang Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Design and synthesis of substituted pyrido[3,2-d]-1,2,3-triazines as potential Pim-1 inhibitors

Yinbo Fan, Kun Li, Min Huang et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10