Jinyu Yang

Design, synthesis and biological evaluation of novel indole derivatives as potential HDAC/BRD4 dual inhibitors and anti-leukemia agents

Gaoliang Cheng, Zhi Wang, Jinyu Yang et al. · Bioorganic Chemistry · 2018 · 49 citations

Medicinal Chemistry, Biochemistry, Medicine +9

Identification of N-(6-mercaptohexyl)-3-(4-pyridyl)-1H-pyrazole-5-carboxamide and its disulfide prodrug as potent histone deacetylase inhibitors with in vitro and in vivo anti-tumor efficacy

Jiachen Wen, Yu Bao, Qun Niu et al. · European Journal of Medicinal Chemistry · 2016 · 48 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Medicine +11

Synthesis, anticancer evaluation and pharmacokinetic study of novel 10-O-phenyl ethers of dihydroartemisinin

Shenglin Luan, Hang Zhong, Xuan Zhao et al. · European Journal of Medicinal Chemistry · 2017 · 33 citations

Medicinal Chemistry, Pharmaceutical Science, Heterocyclic +11

Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1H-pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR study

Jiachen Wen, Qun Niu, Jiang Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 27 citations · Full text

Design, synthesis and biological evaluation of novel hydroxamic acid based histone deacetylase 6 selective inhibitors bearing phenylpyrazol scaffold as surface recognition motif

Jinyu Yang, Gaoliang Cheng, Qihao Xu et al. · Bioorganic & Medicinal Chemistry · 2017 · 23 citations · Full text

Bioorganic Chemistry, Biochemistry, Surface Recognition Motif +10