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Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice

Owen M. Peters, Gabriela Toro Cabrera, Hélène Tran, Tania F. Gendron, Jeanne E. McKeon, Jake Metterville, Alexandra Weiss, Nicholas Wightman, Johnny Salameh, Juhyun Kim,

Neuron · 2015 · 257 citations · 40 references

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A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

Alan E. Renton, Elisa Majounie, Adrian J. Waite et al. · Neuron · 2011 · 4.5K citations · Full text

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The <i>C9orf72</i> GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS

Kohji Mori, Shih‐Ming Weng, Thomas Arzberger et al. · Science · 2013 · 1.3K citations

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Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

Elisa Majounie, Alan E. Renton, Kin Y. Mok et al. · The Lancet Neurology · 2012 · 1.2K citations · Full text

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Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

Peter E.A. Ash, Kevin F. Bieniek, Tania F. Gendron et al. · Neuron · 2013 · 1.1K citations · Full text

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C9orf72 nucleotide repeat structures initiate molecular cascades of disease

Aaron R. Haeusler, Christopher J. Donnelly, Goran Periz et al. · Nature · 2014 · 988 citations · Full text

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