Jake Metterville

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1.4K

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Active since

2015

Affiliations

University of Massachusetts Chan Medical School(Current)

Wave Life Sciences (United States)

Jake Metterville is an author at University of Massachusetts Chan Medical School specializing in life sciences, neurodegenerative diseases, and neurodegeneration.

Publications per year

2015–2024

Publications

TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD

Matthew A. White, Eosu Kim, Amanda Duffy et al. · Nature Neuroscience · 2018 · 298 citations · Full text

Life Sciences, Genetics, Neuroscience +14

Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice

Owen M. Peters, Gabriela Toro Cabrera, Hélène Tran et al. · Neuron · 2015 · 257 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide

Hélène Tran, Michael P. Moazami, Huiya Yang et al. · Nature Medicine · 2021 · 174 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides

Prashant Monian, Chikdu Shivalila, Genliang Lu et al. · Nature Biotechnology · 2022 · 114 citations

Life Sciences, Biotechnology, Molecular Biology +13

Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1 G93A Mice and Nonhuman Primates

Florie Borel, Gwladys Gernoux, Brynn H. Cardozo et al. · Human Gene Therapy · 2015 · 109 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

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