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Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs)

William D. Schmitz, Derek J. Denhart, Allison B. Brenner, Jonathan L. Ditta, Ronald J. Mattson, Gail K. Mattson, Thaddeus F. Molski, John E. Macor

Bioorganic & Medicinal Chemistry Letters · 2005 · 26 citations · 14 references

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14

Synthesis and Structure−Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT<sub>1A</sub> Receptor Agonists and Serotonin Reuptake Inhibitors

Timo Heinrich, Henning Böttcher, R. Gericke et al. · Journal of Medicinal Chemistry · 2004 · 116 citations · Full text

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STRUCTURE ACTIVITY RELATIONS FOR THE INHIBITION OF 5‐HT UPTAKE INTO RAT HYPOTHALAMIC HOMOGENATES BY SEROTONIN AND TRYPTAMINE ANALOGUES

A. S. Horn · Journal of Neurochemistry · 1973 · 92 citations

, , +17

A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Narihiro Toda, Keiko Tago, Shinji Marumoto et al. · Bioorganic & Medicinal Chemistry · 2003 · 89 citations

, , +17

Interactions of Tryptamine Derivatives with Serotonin Transporter Species Variants Implicate Transmembrane Domain I in Substrate Recognition

Erika M. Adkins, Eric L. Barker, Randy Blakely · Molecular Pharmacology · 2001 · 77 citations

, , +17

5-HT Reuptake Inhibitors with 5-HT<sub>1B/1D</sub>Antagonistic Activity:  A New Approach toward Efficient Antidepressants

Lisa Matzen, Christoph van Amsterdam, Wilfried Rautenberg et al. · Journal of Medicinal Chemistry · 2000 · 67 citations · Full text

, , +17