Ronald J. Mattson

An improved method for reductive alkylation of amines using titanium(IV) isopropoxide and sodium cyanoborohydride

Ronald J. Mattson, Kahnie M. Pham, David J. Leuck et al. · The Journal of Organic Chemistry · 1990 · 185 citations

Improved Method, Sodium Cyanoborohydride, Engineering +18

Enantioselective Synthesis of a Highly Potent Selective Serotonin Reuptake Inhibitor. An Application of Imidazolidinone Catalysis to the Alkylation of Indoles with an α,β-Disubstituted α,β-Unsaturated Aldehyde

Dalton King, Zhaoxing Meng, Derek J. Denhart et al. · Organic Letters · 2005 · 123 citations

Asymmetric Catalysis, Medicinal Chemistry, Enantioselective Synthesis +15

A Strategy to Minimize Reactive Metabolite Formation: Discovery of (<i>S</i>)-4-(1-Cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a Potent, Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist

Richard A. Hartz, Vijay T. Ahuja, Xiaoliang Zhuo et al. · Journal of Medicinal Chemistry · 2009 · 54 citations · Full text

Pharmaceutical Science, Metabolic Characterization, Receptor Antagonist +16

[3H]5-carboxamidotryptamine labels multiple high affinity 5-HT1D-like sites in guinea pig brain

Cathy D. Mahle, Henry P. Nowak, Ronald J. Mattson et al. · European Journal of Pharmacology · 1991 · 46 citations

Molecular Neuroscience, Neuroanatomy, Medicine +9

Conformationally restricted homotryptamines 3. Indole tetrahydropyridines and cyclohexenylamines as selective serotonin reuptake inhibitors

Jeffrey A. Deskus, James R. Epperson, C.P. Sloan et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 40 citations · Full text

Molecular Pharmacology, Biochemistry, Functional Selectivity +6