Jonathan L. Ditta - Concepedia

Author

Jonathan L. Ditta

Bristol-Myers Squibb (United States)

Also Known As

Ditta, J.L., J. Ditta, Jonathan Ditta, Jonathan L Ditta, Jonathan L. Ditta

Publications

584

Citations

H-Index

Concepts

All Affiliations

Bristol-Myers Squibb (United States)

About

Jonathan L. Ditta is an author at Bristol-Myers Squibb (United States) specializing in medicine, drug discovery, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	316
2	Natural Sciences	6	6	290
3	Biochemistry	6	6	310
4	Engineering	1	1	42
5	Social Sciences	1	1	26

Jonathan L. Ditta

Publications

515

Citations

H-Index

Page 1

	Year	Citations
2-Aryl-2,2-difluoroacetamide FKBP12 Ligands: Synthesis and X-ray Structural Studies Gene M. Dubowchik, Vivekananda M. Vrudhula, Bireshwar Dasgupta, Organic Letters Chemical BiologyX-ray Structural StudiesHalogenationPharmaceutical ChemistryBiochemistry	2001	103
A Strategy to Minimize Reactive Metabolite Formation: Discovery of (<i>S</i>)-4-(1-Cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a Potent, Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist Richard A. Hartz, Vijay T. Ahuja, Xiaoliang Zhuo, Journal of Medicinal Chemistry Pharmaceutical ScienceMetabolic CharacterizationReceptor AntagonistPharmacotherapyPharmaceutical Chemistry	2009	54
High-Throughput Fluorescence Polarization Method for Identification of FKBP12 Ligands Sagarika Bollini, John J. Herbst, G.T. Gaughan, SLAS DISCOVERY Molecular RecognitionMolecular CharacterizationBiochemistryNatural SciencesBioanalysis	2002	49
Fluoresceinated FKBP12 ligands for a high-throughput fluorescence polarization assay Gene M. Dubowchik, Jonathan L. Ditta, John J. Herbst, Bioorganic & Medicinal Chemistry Letters EngineeringBiochemistrySingle-molecule DetectionChemical ProbeMolecular Recognition	2000	42
In Vitro Intrinsic Clearance-Based Optimization of<i>N</i><sup>3</sup>-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF<sub>1</sub>) Receptor Antagonists Richard A. Hartz, Vijay T. Ahuja, Maria Rafalski, Journal of Medicinal Chemistry	2009	37
Development of New Benzenesulfonamides As Potent and Selective Na<sub>v</sub>1.7 Inhibitors for the Treatment of Pain Yong‐Jin Wu, Jason Guernon, Jianliang Shi, Journal of Medicinal Chemistry	2017	36
Conformationally Restricted Homotryptamines. 2. Indole Cyclopropylmethylamines as Selective Serotonin Reuptake Inhibitors Ronald J. Mattson, John D. Catt, Derek J. Denhart, Journal of Medicinal Chemistry Medicinal ChemistryPsychoactive DrugPotent Hsert BindingBiochemistryIndole Ring	2005	33
Synthesis, Structure−Activity Relationships, and In Vivo Evaluation of<i>N</i><sup>3</sup>-Phenylpyrazinones as Novel Corticotropin-Releasing Factor-1 (CRF<sub>1</sub>) Receptor Antagonists Richard A. Hartz, Vijay T. Ahuja, Argyrios G. Arvanitis, Journal of Medicinal Chemistry	2009	32
Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors Derek J. Denhart, Jeffrey A. Deskus, Jonathan L. Ditta, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBiochemistryFunctional SelectivityMedicineNatural Sciences	2009	29
Discovery of (<i>S</i>)-1-((2′,6-Bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain Guanglin Luo, Ling Chen, Walter A. Kostich, Journal of Medicinal Chemistry	2022	27

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