Concepedia

NK1 antagonists based on seven membered lactam scaffolds

Jason Elliott, Emma Carlson, Gary G. Chicchi, Olivier Dirat, María Domínguez, Ute Gerhard, Richard A. Jelley, A. Brian Jones, Marc M. Kurtz, Kwei Lan Tsao,

Bioorganic & Medicinal Chemistry Letters · 2006 · 18 citations · 6 references

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6

Highly Active and Selective Catalysts for the Formation of α-Aryl Ketones

Joseph M. Fox, Xiaohua Huang, A. Chieffi et al. · Journal of the American Chemical Society · 2000 · 517 citations

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Antiemetic activity of the NK1 receptor antagonist GR205171 in the treatment of established postoperative nausea and vomiting after major gynaecological surgery

Pierre Diemunsch, P. Schoeffler, B. Bryssine et al. · British Journal of Anaesthesia · 1999 · 167 citations · Full text

, , +13

Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor.

Margaret A. Cascieri, E Ber, Tung M. Fong et al. · Molecular Pharmacology · 1992 · 137 citations

, , +12

In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists

N.M.J. Rupniak, F.D. Tattersall, Angela Williams et al. · European Journal of Pharmacology · 1997 · 117 citations

, , +4

Neurokinin antagonists and their potential role in treating depression and other stress disorders

Jeffrey S. Albert · Expert Opinion on Therapeutic Patents · 2004 · 23 citations

, , +17