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Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7-a]pyrrolo[3,4-c]carbazoles

Thomas A. Engler, Kelly Furness, Sushant Malhotra, Concha Sánchez-Martı́nez, Chuan Shih, Walter Xie, Guoxin Zhu, Xun Zhou, Scott E. Conner, Margaret M. Faul,

Bioorganic & Medicinal Chemistry Letters · 2003 · 59 citations · 35 references

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35

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

Alexander Kamb, Nelleke A. Gruis, Jane Weaver-Feldhaus et al. · Science · 1994 · 2.8K citations

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The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway

Michael Shtutman, Jacob Zhurinsky, Inbal Simcha et al. · Proceedings of the National Academy of Sciences · 1999 · 2.2K citations · Full text

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The consensus motif for phosphorylation by cyclin D1‐Cdk4 is different from that for phosphorylation by cyclin A/E‐Cdk2.

Masatoshi Kitagawa, Hideaki Higashi, Hai Kwan Jung et al. · The EMBO Journal · 1996 · 591 citations · Full text

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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling

Ratnam S. Seelan, Ken Taniguchi, Kausilia K. Krishnadath et al. · Nature Genetics · 2000 · 504 citations

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The reaction of vinyl grignard reagents with 2-substituted nitroarenes: A new approach to the synthesis of 7-substituted indoles

Giuseppe Bartoli, Gianni Palmieri, Marcella Bosco et al. · Tetrahedron Letters · 1989 · 327 citations

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