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6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists: Structure–activity exploration of eastern and western parts

Trond Ulven, Paul B. Little, Jean‐Marie Receveur, Thomas M. Frimurer, Øystein Rist, Pia K. Nørregaard, Thomas Högberg

Bioorganic & Medicinal Chemistry Letters · 2005 · 30 citations · 12 references

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12

T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist

Shiro Takekawa, Asano Asami, Yuji Ishihara et al. · European Journal of Pharmacology · 2002 · 201 citations · Full text

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Identification of 2-(4-Benzyloxyphenyl)-<i>N</i>- [1-(2-pyrrolidin-1-yl-ethyl)-1<i>H</i>-indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of Obesity

Andrew J. Souers, Ju Gao, Michael E. Brune et al. · Journal of Medicinal Chemistry · 2005 · 89 citations · Full text

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A Virtual Screening Approach to Finding Novel and Potent Antagonists at the Melanin-Concentrating Hormone 1 Receptor

David E. Clark, Christopher Higgs, Stephen P. Wren et al. · Journal of Medicinal Chemistry · 2004 · 79 citations · Full text

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Discovery of Bicycloalkyl Urea Melanin Concentrating Hormone Receptor Antagonists:  Orally Efficacious Antiobesity Therapeutics

Mark D. McBriar, Henry Guzik, Ruo Xu et al. · Journal of Medicinal Chemistry · 2005 · 72 citations · Full text

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6-Acylamino-2-aminoquinolines as Potent Melanin-Concentrating Hormone 1 Receptor Antagonists. Identification, Structure−Activity Relationship, and Investigation of Binding Mode

Trond Ulven, Thomas M. Frimurer, Jean‐Marie Receveur et al. · Journal of Medicinal Chemistry · 2005 · 55 citations · Full text

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