Shiro Takekawa

T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist

Shiro Takekawa, Asano Asami, Yuji Ishihara et al. · European Journal of Pharmacology · 2002 · 201 citations · Full text

Functional Selectivity, Medicine, Hormonal Receptor +7

Identification and Characterization of a Novel Human Cortistatin-like Peptide

Shoji Fukusumi, Chieko Kitada, Shiro Takekawa et al. · Biochemical and Biophysical Research Communications · 1997 · 166 citations

Pharmacology, Neuropeptide Receptor, Neuropeptides

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

Jonathan C. Schisler, Per Bo Jensen, David G. Taylor et al. · Proceedings of the National Academy of Sciences · 2005 · 155 citations · Full text

Immunology, Glucagon Mrna, Cellular Physiology +17

Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors

Yoshito Terao, Hideo Suzuki, Masato Yoshikawa et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 63 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +13

A single gene directs synthesis of a precursor protein with beta- and alpha-amylase activities in Bacillus polymyxa

Nobuyuki Uozumi, Kensuke Sakurai, Takashi Sasaki et al. · Journal of Bacteriology · 1989 · 52 citations · Full text

Engineering, Alpha-amylase Activities, Enzymatic Modification +16