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Structure-Based design of 2-Arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-Dependent kinases 1 and 2

Kerry L. Sayle, Johanne Bentley, F.Thomas Boyle, AH Calvert, Yuzhu Cheng, Nicola J. Curtin, Jane Endicott, Bernard T. Golding, Ian R. Hardcastle, Philip J. Jewsbury,

Bioorganic & Medicinal Chemistry Letters · 2003 · 71 citations · 6 references

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6

The United Kingdom Chemical Database Service

D. A. Fletcher, Robert F. McMeeking, Donald Maxwell Parkin · Journal of Chemical Information and Computer Sciences · 1996 · 1.1K citations

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Cyclin-Dependent Kinase Inhibitors:  Useful Targets in Cell Cycle Regulation

Thais M. Sielecki, John F. Boylan, Pamela A. Benfield et al. · Journal of Medicinal Chemistry · 2000 · 323 citations

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Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles

Christine E. Arris, F. Thomas Boyle, A. Hilary Calvert et al. · Journal of Medicinal Chemistry · 2000 · 216 citations · Full text

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Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

Thomas G. Davies, Johanne Bentley, Christine E. Arris et al. · Nature Structural Biology · 2002 · 214 citations

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Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with<i>O</i><sup>6</sup>-Substituted Guanine Derivatives

Ashleigh E. Gibson, Christine E. Arris, Johanne Bentley et al. · Journal of Medicinal Chemistry · 2002 · 85 citations · Full text

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