CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

Classification and Regression Trees.

John Van Ryzin, Leo Breiman, Jerome H. Friedman et al. · Journal of the American Statistical Association · 1986 · 21K citations

Computing, Computer Science, Mathematics +13

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8

Finding groups in data: an introduction to cluster analysis

Choice Reviews Online · 1991 · 10.6K citations

Computing, Biostatistics, Data Science +16

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

CpG island methylator phenotype in colorectal cancer

Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota et al. · Proceedings of the National Academy of Sciences · 1999 · 2.5K citations

Medicine, Genetics, Oncology +17