Concepedia

Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling

Yunpeng Zhao, Ben Liu, Qingyun Tian, Jianlu Wei, Brendon Richbourgh

Annals of the Rheumatic Diseases · 2014 · 153 citations · 46 references

DOIFull text

Open access

References

46

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Matt Baker, Ian R. Mackenzie, Stuart Pickering‐Brown et al. · Nature · 2006 · 2.1K citations

, , +11

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

Marc Cruts, Ilse Gijselinck, Julie van der Zee et al. · Nature · 2006 · 1.5K citations

, , +11

The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse

S.S. Glasson, Tracey Blanchet, Elizabeth A. Morris · Osteoarthritis and Cartilage · 2007 · 1.5K citations

, , +11

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

Gehua Zhen, Chunyi Wen, Xiaofeng Jia et al. · Nature Medicine · 2013 · 922 citations · Full text

, , +11

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

Wei Tang, Yi Lu, Qingyun Tian et al. · Science · 2011 · 763 citations · Full text

, , +22