Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

Nancy C. Arbour, Eva Lorenz, Brian C. Schutte et al. · Nature Genetics · 2000 · 2K citations

Life Sciences, Genetics, Immunology +10

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki, Samuele De Minicis, Christoph H. Österreicher et al. · Nature Medicine · 2007 · 1.9K citations

Life Sciences, Immunology, Molecular Biology +14

Score Tests for Association between Traits and Haplotypes when Linkage Phase Is Ambiguous

Daniel J. Schaid, Charles M. Rowland, David E. Tines et al. · The American Journal of Human Genetics · 2002 · 1.8K citations · Full text

Public Health, Biostatistics, Genetics +13

Liver fibrosis

Ramón Bataller · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

Medicine, Cell Biology, Molecular Biology +17

Genetics of gene expression and its effect on disease

Valur Emilsson, Bin Zhang, Amy Leonardson et al. · Nature · 2008 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +12