Concepedia

Cytosolic RNA:DNA hybrids activate the cGAS–STING axis

Arun K. Mankan, Tobias Schmidt, Dhruv Chauhan, Marion Goldeck, Klara Höning, Moritz M. Gaidt, A. V. Kubarenko, Liudmila Andreeva, Karl‐Peter Hopfner, Veit Hornung

The EMBO Journal · 2014 · 352 citations · 33 references

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33

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations

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Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Jiaxi Wu, Lijun Sun, Xiang Chen et al. · Science · 2012 · 2.5K citations

, , +17

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser, Marion Goldeck, Taner Cavlar et al. · Nature · 2013 · 1.6K citations · Full text

, , +12

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

Jesse Summers, William S. Mason · Cell · 1982 · 1.4K citations

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The HADDOCK web server for data-driven biomolecular docking

Sjoerd J. de Vries, Marc van Dijk, Alexandre M. J. J. Bonvin · Nature Protocols · 2010 · 1.4K citations · Full text

, , +14