Karl‐Peter Hopfner

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser, Marion Goldeck, Taner Cavlar et al. · Nature · 2013 · 1.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Structural Biology of Rad50 ATPase

Karl‐Peter Hopfner, Annette Kärcher, David Shin et al. · Cell · 2000 · 913 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Structural mechanism of cytosolic DNA sensing by cGAS

Filiz Çivril, Tobias Deimling, Carina C. de Oliveira Mann et al. · Nature · 2013 · 871 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Modulation of protein properties in living cells using nanobodies

Axel Kirchhofer, Jonas Helma, Katrin Schmidthals et al. · Nature Structural & Molecular Biology · 2009 · 637 citations

Life Sciences, Biochemistry, Cell Biology +8

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

Karl‐Peter Hopfner, Lisa Craig, Gabriel Moncalián et al. · Nature · 2002 · 562 citations

Life Sciences, Genetics, Molecular Biology +9