Concepedia
Gut · 2008 · 554 citations · 42 references
IL23 may play important roles in controlling the differential Th1/Th17 balance in both UC and CD, although Th17 cells may exist in both diseases.
42
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
Timothy R. Mosmann, Holly Cherwinski, M W Bond et al. · The Journal of Immunology · 1986 · 7.5K citations
Adaptive Immune System, T-regulatory Cell, Cellular Immunology +19
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5K citations · Full text
Inflammation, Cytokine, Lymphocyte Development +9
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology · 2005 · 4.6K citations
Lymphocyte Development, Immune Cell Development, Adaptive Immune System +10
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text
Inflammation, Autoimmune Disease, Tissue Inflammation +11
Transforming growth factor-β induces development of the TH17 lineage
Paul R. Mangan, Laurie E. Harrington, Darrell B. O’Quinn et al. · Nature · 2006 · 3K citations
Developmental Biology, Th17 Lineage, Cell Proliferation +3