Enzymatic Activity of Lysosomal Carboxypeptidase (Cathepsin) A Is Required for Proper Elastic Fiber Formation and Inactivation of Endothelin-1 - Concepedia

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Enzymatic Activity of Lysosomal Carboxypeptidase (Cathepsin) A Is Required for Proper Elastic Fiber Formation and Inactivation of Endothelin-1

108

Citations

35

References

2008

Year

Volkan Seyrantepe, Aleksander Hinek, Junzheng Peng, Michael Fedjaev, Sheila Ernest, Yoshito Kadota, Maryssa Canuel, Kohji Itoh, Carlos R. Morales, Julie L. Lavoie,

Abstract

Our results provide the first evidence that CathA acts in vivo as an endothelin-1-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation.

References

	Year	Citations

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