Concepedia

K-rasG12V transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis

Yumin Hu, Weiqin Lu, Gang Chen, Peng Wang, Zhao Chen, Yan Zhou, Marcia A. Ogasawara, Dunyaporn Trachootham, Hélène Pelicano, Paul J. Chiao,

Cell Research · 2011 · 302 citations · 24 references

DOI

Concepts

References

24

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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ras oncogenes in human cancer: a review.

Joyce Bos · PubMed · 1989 · 5.1K citations

, , +17

On Respiratory Impairment in Cancer Cells

Otto Warbürg · Science · 1956 · 3.2K citations

, , +13

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate

Dunyaporn Trachootham, Yan Zhou, Hui Zhang et al. · Cancer Cell · 2006 · 1.1K citations · Full text

, , +8

c-Myc Can Induce DNA Damage, Increase Reactive Oxygen Species, and Mitigate p53 Function

Omid Vafa, Mark Wade, S Kern et al. · Molecular Cell · 2002 · 871 citations · Full text

, , +16