Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate

Dunyaporn Trachootham, Yan Zhou, Hui Zhang, +8

Cancer Cell

Signal TransductionCell RegulationSelective KillingOncogenic AgentApoptosis +9

Inhibition of Glycolysis in Cancer Cells: A Novel Strategy to Overcome Drug Resistance Associated with Mitochondrial Respiratory Defect and Hypoxia

Rui‐Hua Xu, Hélène Pelicano, Yan Zhou, +5

Cancer Research

Mitochondrial Respiratory DefectIncreased GlycolysisOncologyNovel StrategyMitochondrial Function +13

Inhibition of Mitochondrial Respiration

Hélène Pelicano, Feng Li, Yan Zhou, +5

Journal of Biological Chemistry

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

Yan Zhou, Elizabeth O. Hileman, William Plunkett, +2

Blood

Mitochondrial Manganese-Superoxide Dismutase Expression in Ovarian Cancer

Yumin Hu, Daniel Rosen, Yan Zhou, +4

Journal of Biological Chemistry

Mitochondrial FunctionBiochemistryLipid PeroxidationSuperoxide DismutasesImportant Antioxidant Enzymes +9

Mitochondrial Dysfunction and Reactive Oxygen Species Imbalance Promote Breast Cancer Cell Motility through a CXCL14-Mediated Mechanism

Hélène Pelicano, Weiqin Lu, Yan Zhou, +4

Cancer Research

Breast OncologyMitochondrial DysfunctionReactive Oxygen SpeciesCancer BiologyTumor Biology +14

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism

Dunyaporn Trachootham, Hui Zhang, Wan Zhang, +9

Blood

OSW-1: a Natural Compound With Potent Anticancer Activity and a Novel Mechanism of Action

Yan Zhou, Celia Garcı́a-Prieto, Dennis Carney, +12

JNCI Journal of the National Cancer Institute

Effective Killing of Leukemia Cells by the Natural Product OSW-1 through Disruption of Cellular Calcium Homeostasis

Celia Garcı́a-Prieto, Kausar Begam Riaz Ahmed, Zhao Chen, +7

Journal of Biological Chemistry

ApoptosisCell DeathLeukemia CellsCellular PharmacologyCancer Biology +17

Mechanism study of Aconitum-induced neurotoxicity in PC12 cells: Involvement of dopamine release and oxidative damage

Yinglan Zhao, Qian Bu, Yan Zhou, +5

NeuroToxicology

Pc12 CellsMedicineCell DeathToxicologyNeuroprotection +7