Concepedia

Mathematical analysis of the pharmacokinetic–pharmacodynamic (PKPD) behaviour of monoclonal antibodies: Predicting in vivo potency

Philip J. Aston, Gianne Derks, Adewale Raji, Balaji Agoram, Piet H. van der Graaf

Journal of Theoretical Biology · 2011 · 50 citations · 12 references

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Concepts

References

12

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

Erwin De Genst, Karen Silence, Klaas Decanniere et al. · Proceedings of the National Academy of Sciences · 2006 · 666 citations · Full text

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General Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, William J. Jusko · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 587 citations

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Quasi-Equilibrium Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, Wojciech Krzyżański · Pharmaceutical Research · 2005 · 222 citations

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A mechanism‐based binding model for the population pharmacokinetics and pharmacodynamics of omalizumab

Naoto Hayashi, Yuko Tsukamoto, William M. Sallas et al. · British Journal of Clinical Pharmacology · 2006 · 171 citations · Full text

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The development of nanobodies for therapeutic applications.

Femke Van Bockstaele, Josefin-Beate Holz, Hilde Revets · PubMed · 2009 · 145 citations

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