Concepedia

Karen Silence

KS

5

Publications

1.1K

Citations

5

H-Index

2005

Active since

Affiliations

Vrije Universiteit Brussel(Current)

Ablynx (Belgium)

Vlaams Instituut voor Biotechnologie

Central Veterinary Research Laboratory

Karen Silence is an author at Vrije Universiteit Brussel specializing in cancer research, molecular oncology, and cancer therapeutics.

Top concepts

Publications per year

2005–2017

5

Publications

5

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

Erwin De Genst, Karen Silence, Klaas Decanniere et al. · Proceedings of the National Academy of Sciences · 2006 · 653 citations · Full text

Formatted anti–tumor necrosis factor α VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen‐induced arthritis

Ken Coppieters, Torsten Dreier, Karen Silence et al. · Arthritis & Rheumatism · 2006 · 296 citations

Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions

Els Beirnaert, Aline Desmyter, Silvia Spinelli et al. · Frontiers in Immunology · 2017 · 85 citations · Full text

Strong in Vivo Maturation Compensates for Structurally Restricted H3 Loops in Antibody Repertoires

Erwin De Genst, Karen Silence, Mehdi Arbabi Ghahroudi et al. · Journal of Biological Chemistry · 2005 · 55 citations · Full text

A phase I, first-in-human study of argx-111, a monoclonal antibody targeting c-met in patients with solid tumors.

Philippe Aftimos, Philippe Barthélémy, Christian Rolfo et al. · Journal of Clinical Oncology · 2015 · 15 citations

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