Inflammasome activation has an important role in the development of spontaneous colitis

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Jean‐Pierre Hugot, Mathias Chamaillard, Habib Zouali et al. · Nature · 2001 · 5.6K citations

Inflammation, Autoimmune Disease, Immunology +6

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Yasunori Ogura, Denise K. Bonen, Naohiro Inohara et al. · Nature · 2001 · 5K citations · Full text

Inflammation, Autoimmune Disease, Disease Mechanism +8

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel et al. · Cell · 2009 · 4.4K citations · Full text

Dysbiosis, Mucosal Immunology, Microbiology +5

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

Inflammation, Cytokine, Autoimmune Disease +6

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Henao‐Mejia, Eran Elinav, Chengcheng Jin et al. · Nature · 2012 · 2.4K citations

Inflammation, Inflammasome-mediated Dysbiosis, Immunology +6