A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Yasunori Ogura, Denise K. Bonen, Naohiro Inohara, +14

Nature

InflammationAutoimmune DiseaseDisease MechanismPathogenesisImmunology +6

Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract

Koichi S. Kobayashi, Mathias Chamaillard, Yasunori Ogura, +4

Science

Nod2 ProteinInnate Immune SystemImmune RegulationImmunologyPathology +17

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

Naohiro Inohara, Yasunori Ogura, Ana Fontalba, +11

Journal of Biological Chemistry

InflammationMolecular ImmunologyAntimicrobial Drug DiscoveryAutoimmune DiseaseMucosal Immunology +13

Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB

Yasunori Ogura, Naohiro Inohara, Adalberto Benito, +3

Journal of Biological Chemistry

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

Mathias Chamaillard, Masahito Hashimoto, Yasuo Horie, +12

Nature Immunology

Essential RoleBiochemistryBacteriologyMicrobiologyMolecular Microbiology +2

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

Luigi Franchi, Amal O. Amer, Mathilde Body–Malapel, +9

Nature Immunology

InflammationCytokineMicrobial PathogensPathogenesisImmunology +12

The NLR Gene Family: A Standard Nomenclature

Jenny P.‐Y. Ting, Ruth C. Lovering, Emad S. Alnemri, +21

Immunity

Nlr Gene FamilyGene Sequence AnnotationGeneticsGene StructureMolecular Genetics +4

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

Koichi S. Kobayashi, Naohiro Inohara, Lorraine D. Hernandez, +5

Nature

InflammationSignal TransductionAllergyReceptor Tyrosine KinaseInnate Immune System +11

Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB

Naohiro Inohara, Takeyoshi Koseki, Luis del Peso, +8

Journal of Biological Chemistry

Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA

Thirumala‐Devi Kanneganti, Mathilde Body–Malapel, Amal O. Amer, +8

Journal of Biological Chemistry

Viral ReplicationIl-18 ProductionImmunologyCell DeathViral Infection +18