Concepedia

Defects of mitogen-activated protein kinase in ICOS signaling pathway lead to CD4+ and CD8+ T-cell dysfunction in patients with active SLE

Gang Cai, Yang Jiahui, Huaizhou Wang, Cai Qing

Cellular Immunology · 2009 · 16 citations · 20 references

Concepts

Life SciencesCell BiologyImmunologyCell SignalingImmunopathologySignal TransductionImmune Cell SignalingImmune DysfunctionImmune SignalingInflammatory SignalingProtein Kinase CascadesT Cell ActivationCd4 T Cell ActivationCd8 T Cell ActivationKinase Cascades In T Cell ActivationMitogen-activated Protein Kinase KinaseMitogen-activated Protein Kinase PathwaysMitogen-activated Protein Kinase SignalingMitogen-activated Protein Kinase Signaling Disruption

References

20

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

Frank C. Arnett, Steven M. Edworthy, D. Blöch et al. · Arthritis & Rheumatism · 1988 · 19.9K citations

Medicine, Clinical Sciences, Internal Medicine +12

The 1982 revised criteria for the classification of systemic lupus erythematosus

Eng M. Tan, Alan S. Cohen, James F. Fries et al. · Arthritis & Rheumatism · 1982 · 14.6K citations

Life Sciences, Immunology, Internal Medicine +14

Derivation of the sledai. A disease activity index for lupus patients

Claire Bombardier, Dafna D. Gladman, Murray B. Urowitz et al. · Arthritis & Rheumatism · 1992 · 4.6K citations

Pharmacy, Clinical Sciences, Internal Medicine +17

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Andreas Hutloff, Anna‐Maria Dittrich, Katja C. Beier et al. · Nature · 1999 · 1.5K citations

Life Sciences, Immunology, Molecular Biology +12

B70 antigen is a second ligand for CTLA-4 and CD28

Miyuki Azuma, Daisuke Ito, Hideo Yagita∥ et al. · Nature · 1993 · 915 citations

Life Sciences, Immunology, Molecular Biology +14