B70 antigen is a second ligand for CTLA-4 and CD28

Miyuki Azuma, Daisuke Ito, Hideo Yagita∥, +4

Nature

Molecular ImmunologyAutoimmune DiseaseAllergyAdaptive Immune SystemImmunology +8

CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

Lewis L. Lanier, S O'Fallon, Chamorro Somoza, +5

The Journal of Immunology

Osteopontin as a Mediator of NKT Cell Function in T Cell-Mediated Liver Diseases

Hongyan Diao, Shigeyuki Kon, Kazuya Iwabuchi, +14

Immunity

InflammationNkt Cell FunctionAutoimmune DiseaseHepatologyLiver Physiology +13

Ferric ions involved in the flower color development of the Himalayan blue poppy, Meconopsis grandis

Kumi Yoshida, S. Kitahara, Daisuke Ito, +1

Phytochemistry

BiologyPlant BiologyEngineeringBotanyNatural Sciences +8

Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications

Yūji Yoshida, Atsushi Ogata, Sujin Kang, +16

Arthritis & Rheumatology

Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats

Daisuke Ito, Pengyu Cao, Takaaki Kakihana, +9

PLoS ONE

Zucker Diabetic RatsInsulin SignalingObesityMetabolic SyndromeKinesiology +18

Minimum neuron density for synchronized bursts in a rat cortical culture on multi-electrode arrays

Daisuke Ito, Hiroki Tamate, Masaichi Nagayama, +3

Neuroscience

NeurodynamicsNeurophysiologyCellular NeuroscienceComputational NeurosciencePhysiology +10

All-<i>Trans</i> Retinoic Acid Induces Differentiation of Ducts and Endocrine Cells by Mesenchymal/Epithelial Interactions in Embryonic Pancreas

Sidhartha Tulachan, Ryuichiro Doi, Yoshiya Kawaguchi, +10

Diabetes

Retinoic AcidCell ProliferationCell SpecializationCellular PhysiologyInsulin Signaling +19

Elevation of Sema4A Implicates Th Cell Skewing and the Efficacy of IFN-β Therapy in Multiple Sclerosis

Yuji Nakatsuji, Tatsusada Okuno, M. Moriya, +19

The Journal of Immunology

Hypoxia induces resistance to 5-fluorouracil in oral cancer cells via G1 phase cell cycle arrest

Sayaka Yoshiba, Daisuke Ito, Tatsuhito Nagumo, +3

Oral Oncology

Hypoxia Induces ResistanceOncologyOral Cancer CellsMedicineCancer Biology +7