Concepedia

BacMam-Enabled LanthaScreen® Cellular Assays for PI3K/Akt Pathway Compound Profiling in Disease-Relevant Cell Backgrounds

Coby B. Carlson, Michael J. Mashock, Kun Bi

SLAS DISCOVERY · 2010 · 12 citations · 13 references

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References

13

Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis

Montserrat Camps, Thomas Rückle, Hong Ji et al. · Nature Medicine · 2005 · 751 citations

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Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines

Kaname Nakatani, Devon A. Thompson, Andreas Barthel et al. · Journal of Biological Chemistry · 1999 · 474 citations · Full text

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Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector

J. Patrick Condreay, Sam M. Witherspoon, William C. Clay et al. · Proceedings of the National Academy of Sciences · 1999 · 421 citations

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RETRACTED: Breast Tumor Cells with PI3K Mutation or HER2 Amplification Are Selectively Addicted to Akt Signaling

Qing‐Bai She, Sarat Chandarlapaty, Qing Ye et al. · PLoS ONE · 2008 · 317 citations · Full text

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Potent and selective inhibitors of Akt kinases slow the progress of tumors <i>in vivo</i>

Yan Luo, Alexander R. Shoemaker, Xuesong Liu et al. · Molecular Cancer Therapeutics · 2005 · 244 citations · Full text

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