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Synthesis and anti-influenza evaluation of orally active bicyclic ether derivatives related to zanamivir

Takeshi Masuda, Satoshi Shibuya, Masami Arai, Shuku Yoshida, Takanori Tomozawa, Akiko Ohno, Makoto Yamashita, Takeshi Honda

Bioorganic & Medicinal Chemistry Letters · 2003 · 55 citations · 11 references

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11

Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature · 1993 · 1.9K citations

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Characterization of temperature sensitive influenza virus mutants defective in neuraminidase

Peter Palese, Kiyotake Tobita, Masahiro Ueda et al. · Virology · 1974 · 796 citations

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BCX-1812 (RWJ-270201):  Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design

Y.S. Babu, Pooran Chand, Shanta Bantia et al. · Journal of Medicinal Chemistry · 2000 · 378 citations · Full text

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Inhibition of Influenza Virus Replication in Tissue Culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): Mechanism of Action

Peter Palese, Richard W. Compans · Journal of General Virology · 1976 · 368 citations

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Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4<i>H</i>-pyran-6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Journal of Medicinal Chemistry · 1998 · 343 citations · Full text

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