Concepedia

Evaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19

Tatyana Zvyaga, Shu‐Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew J. Wagner, Anjaneya Chimalakonda, A. David Rodrigues

Drug Metabolism and Disposition · 2012 · 123 citations · 44 references

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44

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

Alan R. Shuldiner · JAMA · 2009 · 1.5K citations · Full text

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Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

Miho Kazui, Yumi Nishiya, Tomoko Ishizuka et al. · Drug Metabolism and Disposition · 2009 · 821 citations

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The effects of age and liver disease on the disposition and elimination of diazepam in adult man.

Ulrich Klotz, George R. Avant, Anastacio M. Hoyumpa et al. · Journal of Clinical Investigation · 1975 · 696 citations · Full text

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COMPARISON OF INHIBITORY EFFECTS OF THE PROTON PUMP-INHIBITING DRUGS OMEPRAZOLE, ESOMEPRAZOLE, LANSOPRAZOLE, PANTOPRAZOLE, AND RABEPRAZOLE ON HUMAN CYTOCHROME P450 ACTIVITIES

Xueqing Li, Tommy B. Andersson, Marie M. Ahlström et al. · Drug Metabolism and Disposition · 2004 · 642 citations

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VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES

Robert L. Walsky, R. Scott Obach · Drug Metabolism and Disposition · 2004 · 504 citations

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