Miho Kazui

Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

Miho Kazui, Yumi Nishiya, Tomoko Ishizuka et al. · Drug Metabolism and Disposition · 2009 · 821 citations

Medicine, Biochemistry, Pharmacology +17

The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2

Eric T. Williams, Karen O. Jones, G. Douglas Ponsler et al. · Drug Metabolism and Disposition · 2008 · 127 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel

Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara et al. · Drug Metabolism and Disposition · 2009 · 122 citations

Medicine, Biochemistry, Pharmacology +16

Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs.

Kenji Kawai, Y Kawasaki-Tokui, Tomoyo ODAKA et al. · PubMed · 1997 · 99 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Comparison of Human Cytochrome P450 Inhibition by the Thienopyridines Prasugrel, Clopidogrel, and Ticlopidine

Katsunobu Hagihara, Yumi Nishiya, Atsushi Kurihara et al. · Drug Metabolism and Pharmacokinetics · 2008 · 74 citations

Medicine, Pharmacokinetics, Pharmacology +13