Yumi Nishiya

Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

Miho Kazui, Yumi Nishiya, Tomoko Ishizuka et al. · Drug Metabolism and Disposition · 2009 · 821 citations

Medicine, Biochemistry, Pharmacology +17

Comparison of Human Cytochrome P450 Inhibition by the Thienopyridines Prasugrel, Clopidogrel, and Ticlopidine

Katsunobu Hagihara, Yumi Nishiya, Atsushi Kurihara et al. · Drug Metabolism and Pharmacokinetics · 2008 · 74 citations

Medicine, Pharmacokinetics, Pharmacology +13

Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel

Yumi Nishiya, Katsunobu Hagihara, Atsushi Kurihara et al. · Xenobiotica · 2009 · 65 citations

Medicine, Pharmacokinetics, Pharmacology +17

Mechanism-Based Inhibition of Human Cytochrome P450 2B6 by Ticlopidine, Clopidogrel, and the Thiolactone Metabolite of Prasugrel

Yumi Nishiya, Katsunobu Hagihara, Takashi Ito et al. · Drug Metabolism and Disposition · 2008 · 62 citations

Medicine, Pharmacokinetics, Pharmacology +17

A Potent Blood–Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model

Yukino Machida, Makoto Nakagawa, Hironori Matsunaga et al. · Molecular Cancer Therapeutics · 2019 · 55 citations · Full text

Medicine, Oncology, Pharmacology +15