Yukino Machida

Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma

Makoto Nakagawa, Fumihiko Nakatani, Hironori Matsunaga et al. · Oncogene · 2019 · 69 citations · Full text

Medicine, Oncology, Pharmacology +14

A Potent Blood–Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model

Yukino Machida, Makoto Nakagawa, Hironori Matsunaga et al. · Molecular Cancer Therapeutics · 2019 · 55 citations · Full text

Medicine, Oncology, Pharmacology +15

Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line

Masafumi Noguchi, Susumu Kohno, Anna Pellattiero et al. · Cell Death and Disease · 2023 · 42 citations · Full text

Medicine, Oncology, Pharmacology +17

Hepatic enzyme activities and plasma insulin concentrations in diabetic herbivorous voles

Toshiro Arai, Yukino Machida, Minoru Sasaki et al. · Veterinary Research Communications · 1989 · 38 citations

Life Sciences, Animal Sciences, Endocrinology +12

Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma

Makoto Nakagawa, Masayuki Yamaguchi, Makoto Endo et al. · Journal of bone oncology · 2022 · 16 citations · Full text

Medicine, Cancer Biology, Oncology +11