Molecular Composition of Sub‐stoichiometrically Labeled α‐Synuclein Oligomers Determined by Single‐Molecule Photobleaching

Abstract

Bleaching proteins: Single-molecule photobleaching approaches and sub-stoichiometric labeling with fluorophores give insight into the number of monomers that form a specific α-synuclein oligomer. The results show that this α-synuclein oligomer is present as a single, well-defined species consisting of 31 monomers.