A Concise Total Synthesis of the Notoamides C and D

Abstract

A unique oxidation: The first total synthesis of the prenylated indole alkaloids notoamide C and D was accomplished by using a biomimetic oxidation pathway. Oxidation of the putative biosynthetic precursor 1 was achieved in a one-pot reaction to afford notoamide C, its epimer, and notoamide D (see scheme). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z604377_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.