Concepedia

Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial

Nicola Normanno, Anna Maria Rachiglio, Matilde Lambiase, Erika Martinelli, Francesca Fenizia, Ciro Esposito, Cristin Roma, Teresa Troiani, Daniele Rizzi, Fabiana Tatangelo,

Annals of Oncology · 2015 · 145 citations · 13 references

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13

Comprehensive molecular characterization of human colon and rectal cancer

Nature · 2012 · 8.5K citations · Full text

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Panitumumab–FOLFOX4 Treatment and <i>RAS</i> Mutations in Colorectal Cancer

Jean‐Yves Douillard, Kelly S. Oliner, Salvatore Siena et al. · New England Journal of Medicine · 2013 · 2.2K citations · Full text

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

Anirudh Prahallad, Chong Sun, Sidong Huang et al. · Nature · 2012 · 2K citations · Full text

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FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial

Volker Heinemann, Ludwig Fischer von Weikersthal, Thomas Decker et al. · The Lancet Oncology · 2014 · 1.7K citations

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A Big Bang model of human colorectal tumor growth

Andrea Sottoriva, Haeyoun Kang, Zhicheng Ma et al. · Nature Genetics · 2015 · 1K citations

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