A Big Bang model of human colorectal tumor growth

Andrea Sottoriva, Haeyoun Kang, Zhicheng Ma, +8

Nature Genetics

Tumor BiologyBig Bang ModelMedicineColorectal CancerPathology +4

Quantitative evidence for early metastatic seeding in colorectal cancer

Zheng Hu, Jie Ding, Zhicheng Ma, +12

Nature Genetics

Quantitative EvidenceMedicineColorectal CancerPathologyOncology +1

Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases

Zheng Hu, Zan Li, Zhicheng Ma, +1

Nature Genetics

Tumor BiologyPaired Primary TumorsMalignant DiseaseTumor HeterogeneityMedicine +9

Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells

Jo‐Ling Liao, Juehua Yu, Kevin Huang, +9

Human Molecular Genetics

Adult Stem CellAge-related Macular DegenerationRetinal TherapiesStem-cell-derived Rpe CellsCell Specialization +17

Between-region genetic divergence reflects the mode and tempo of tumor evolution

Ruping Sun, Zheng Hu, Andrea Sottoriva, +6

Nature Genetics

Developmental BiologySomatic VariantBetween-region Genetic DivergenceTumor HeterogeneityMedicine +7

Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response

Katherine McNamara, Jennifer L. Caswell‐Jin, Rohan P. Joshi, +12

Nature Cancer

Breast OncologyOncologyEndocrine-related CancerNeoadjuvant TherapyMedicine +7

Repression of Retrotransposal Elements in Mouse Embryonic Stem Cells Is Primarily Mediated by a DNA Methylation-independent Mechanism

Leah Hutnick, Xinhua Huang, Tao-Chuan Loo, +2

Journal of Biological Chemistry

Epigenetic ChangeGeneticsDna MethylationRetrotransposal ElementsCell Specialization +17

Deterministic evolution and stringent selection during preneoplasia

Kasper Karlsson, Moritz J. Przybilla, Eran Kotler, +15

Nature

Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy

Jennifer L. Caswell‐Jin, Katherine McNamara, Johannes G. Reiter, +17

Nature Communications

Periostin identified as a potential biomarker of prostate cancer by iTRAQ-proteomics analysis of prostate biopsy

Chuanyu Sun, Chao Song, Zhicheng Ma, +7

Proteome Science