Endosomal abnormalities related to amyloid precursor protein in cholesterol treated cerebral cortex neuronal cells derived from trisomy 16 mice, an animal model of Down syndrome

Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

Robert Ehehalt, Patrick Keller, Christian Haass et al. · The Journal of Cell Biology · 2003 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Intraneuronal Aβ42 Accumulation in Human Brain

Gunnar K. Gouras, Julia Tsai, Jan Näslund et al. · American Journal Of Pathology · 2000 · 994 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester et al. · Neurobiology of Disease · 2000 · 994 citations · Full text

Life Sciences, Biochemistry, Neurology +14

Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome

Anne M. Cataldo, Corrinne M. Peterhoff, Juan C. Troncoso et al. · American Journal Of Pathology · 2000 · 850 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down syndrome

Anne M. Cataldo, Suzana Petanceska, Nicole B. Terio et al. · Neurobiology of Aging · 2004 · 362 citations

Life Sciences, Neurology, Neuroscience +14