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Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment

L. Ranganath, Anna M. Milan, Andrew T. Hughes, John Dutton, Richard J. Fitzgerald, Michael Briggs, Helen Bygott, Eftychia Eirini Psarelli, Trevor F. Cox, James A. Gallagher,

Annals of the Rheumatic Diseases · 2014 · 157 citations · 15 references

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References

15

Natural History of Alkaptonuria

Chanika Phornphutkul, Wendy J. Introne, Monique B. Perry et al. · New England Journal of Medicine · 2002 · 655 citations · Full text

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Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase

Sandra Lindstedt · The Lancet · 1992 · 641 citations

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THE NATURE OF THE DEFECT IN TYROSINE METABOLISM IN ALCAPTONURIA

Bert N. La Du, Vincent G. Zannoni, Leonard Laster et al. · Journal of Biological Chemistry · 1958 · 356 citations · Full text

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Biochemical, pathologic and clinical aspects of alcaptonuria, ochronosis and ochronotic arthropathy

William M. O’Brien, Bert N. La Du, Joseph J. Bunim · The American Journal of Medicine · 1963 · 317 citations

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A 3-year randomized therapeutic trial of nitisinone in alkaptonuria

Wendy J. Introne, Monique B. Perry, James Troendle et al. · Molecular Genetics and Metabolism · 2011 · 203 citations · Full text

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