Andrew T. Hughes

Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment

L. Ranganath, Anna M. Milan, Andrew T. Hughes et al. · Annals of the Rheumatic Diseases · 2014 · 157 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +6

Validation of a rapid and sensitive high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds

Laura Else, Victoria Watson, John Tjia et al. · Journal of Chromatography B · 2010 · 141 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +16

Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial

L. Ranganath, Eftychia Eirini Psarelli, Jean-Baptiste Arnoux et al. · The Lancet Diabetes & Endocrinology · 2020 · 123 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +3

Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre

L. Ranganath, Milad Khedr, Anna M. Milan et al. · Molecular Genetics and Metabolism · 2018 · 104 citations · Full text

Medicine, Internal Medicine, Molecular Pathology +1

Urine homogentisic acid and tyrosine: Simultaneous analysis by liquid chromatography tandem mass spectrometry

Andrew T. Hughes, Anna M. Milan, Peter Christensen et al. · Journal of Chromatography B · 2014 · 64 citations

Natural Sciences, Biochemistry, Pharmaceutical Analysis +16