Concepedia

Role for Nuclear Factor-κB and Signal Transducer and Activator of Transcription 1/Interferon Regulatory Factor-1 in Cytokine-Induced Endothelin-1 Release in Human Vascular Smooth Muscle Cells

Mandy Woods, Elizabeth G. Wood, Sonya C. Bardswell, David Bishop‐Bailey, Stewart Barker, Stephen J. Wort, Jane A. Mitchell, Timothy D. Warner

Molecular Pharmacology · 2003 · 60 citations · 34 references

Concepts

Life SciencesCardiologyPhysiologyCell SignalingSignal TransductionTranscriptional RegulationCardiovascular DiseaseCardiovascular PhysiologyCytokine BiologyCytokine SignalingInflammatory MediatorsPulmonary HypertensionCytokine-mediated Vascular ResponsesEndothelin-mediated VasoconstrictionIntracellular Signaling PathwaysNuclear Factor Kappa B ActivationVascular Smooth Muscle RegulationVascular Tone Modulation

References

34

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

Vito J. Palombella, Oliver J. Rando, Alfred L. Goldberg et al. · Cell · 1994 · 2.1K citations

Life Sciences, Biochemistry, Molecular Biology +11

THE SMOOTH MUSCLE CELL

Russell Ross · The Journal of Cell Biology · 1971 · 1.6K citations · Full text

Life Sciences, Endocrinology, Physiology +17

Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL

T. Heinemeyer · Nucleic Acids Research · 1998 · 1.5K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

Zhe Chen, Jeremiah Hagler, Vito J. Palombella et al. · Genes & Development · 1995 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

Thomas Henkel, Thomas Machleidt, Irit Alkalay et al. · Nature · 1993 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +12