Preconcentration of Rutin at a Poly Glutamic Acid Modified Electrode and its Determination by Square Wave Voltammetry

Abstract

Abstract The voltammetric determination of rutin in 0.04 mol l−1 B‐R buffer (pH 4.0) by square wave voltammograms (+0.41 V vs. Ag/AgCl(sat.)) at a poly glutamic acid modified glassy carbon electrode was found to be several orders of magnitude lower than that on a bare glassy carbon electrode. Rutin can be preconcentrated on the films of poly glutamic acid and presented linear relationship from concentration of 7×10−7 to 1×10−5 mol l−1 in 0.04 mol l−1 B‐R buffer pH 4.0. The method was successfully applied to the determination of rutin in pharmaceutical formulation without any pretreatment.