Concepedia

Synthesis and evaluation of the anti-proliferative and NF-κB activities of a library of simplified tylophorine analogs

Micah J. Niphakis, Bryant Gay, Kwon Ho Hong, Nicholas P. Bleeker, Gunda I. Georg

Bioorganic & Medicinal Chemistry · 2012 · 18 citations · 26 references

Concepts

PharmacyMedicinal ChemistryPharmacologyDrug DesignDrug DiscoveryStructure-activity RelationshipsChemical Library DesignCombinatorial SynthesisDiversity-oriented SynthesisLibrary DesignLigand-based DesignStructure-activity Relationship AnalysisBioactive Compound LibrariesChemical Library SynthesisChemical Synthesis Of AnaloguesMedicinal Chemistry ApplicationsNf-κb Signaling

References

26

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

Frank Lovering, Jack Bikker, Christine Humblet · Journal of Medicinal Chemistry · 2009 · 4.4K citations

Pharmacy, Chemistry, Medicinal Chemistry +8

The Alkaloids, Chemistry and Pharmacology

European Journal of Medicinal Chemistry · 1992 · 916 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Efficient oxidative biaryl coupling reaction of phenol ether derivatives using hypervalent iodine(III) reagents

Hirofumi Tohma, Hironori Morioka, Shinobu Takizawa et al. · Tetrahedron · 2001 · 187 citations

Natural Sciences, Chemical Engineering, Chemistry +11

Total Syntheses of the Tylophora Alkaloids Cryptopleurine, (−)‐Antofine, (−)‐Tylophorine, and (−)‐Ficuseptine C

Alois Fürstner, Jason W. J. Kennedy · Chemistry - A European Journal · 2006 · 174 citations

Medicine, Medicinal Chemistry, Pharmacology +7

The Indolizidine Alkaloids

E Gellert · Journal of Natural Products · 1982 · 154 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7