Nicholas P. Bleeker

Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4<i>H</i>-chromene-3-carboxylate (CXL017) and Its Analogues

Sonia G. Das, Balasubramanian Srinivasan, David Hermanson et al. · Journal of Medicinal Chemistry · 2011 · 59 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Structure–Activity Relationship (SAR) Study of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4<i>H</i>-chromene-3-carboxylate (CXL017) and the Potential of the Lead against Multidrug Resistance in Cancer Treatment

G. Aridoss, Bo Zhou, David Hermanson et al. · Journal of Medicinal Chemistry · 2012 · 47 citations · Full text

Pharmacy, Oncology, Pharmacology +14

A Novel SERCA Inhibitor Demonstrates Synergy with Classic SERCA Inhibitors and Targets Multidrug-Resistant AML

Nicholas P. Bleeker, Rǎzvan L. Cornea, David D. Thomas et al. · Molecular Pharmaceutics · 2013 · 31 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4<i>H</i>-chromene-3-carboxylate (CXL017): A Novel Scaffold That Resensitizes Multidrug Resistant Leukemia Cells to Chemotherapy

Sonia G. Das, David Hermanson, Nicholas P. Bleeker et al. · ACS Chemical Biology · 2012 · 25 citations

Medicine, Oncology, Pharmacology +14

Synthesis and evaluation of the anti-proliferative and NF-κB activities of a library of simplified tylophorine analogs

Micah J. Niphakis, Bryant Gay, Kwon Ho Hong et al. · Bioorganic & Medicinal Chemistry · 2012 · 18 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14