Concepedia

Combinatorial Synthesis

Combinatorial Synthesis is a systematic synthetic methodology in medicinal chemistry that generates a diverse array of chemical compounds through the parallel or sequential combination of multiple building blocks, distinguished by its capacity to rapidly produce large libraries of structurally related molecules for high-throughput biological evaluation.

3.8K

Publications

222.2K

Citations

13.1K

Authors

2.1K

Institutions

Publications per year

2017–2026

747

Parents

Children

Publications

3.8K

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless · Angewandte Chemie International Edition · 2001 · 13K citations

, , +17

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless · Angewandte Chemie International Edition · 2001 · 9.3K citations · Full text

, , +17

The Atom Economy—A Search for Synthetic Efficiency

BM Trost · Science · 1991 · 4.7K citations

, , +16

Multicomponent Reactions with Isocyanides

Alexander Dömlingꝉ, Ivar Ugi · Angewandte Chemie International Edition · 2000 · 4K citations

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Light-Directed, Spatially Addressable Parallel Chemical Synthesis

Stephen P. A. Fodor, Jill Read, Michael C. Pirrung et al. · Science · 1991 · 2.7K citations

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1–5 of 3.8K

Authors

13.1K

  1. JK
    Jeremy K. M. Sanders

    University of Cambridge, United Kingdom

    31 publications · 3K citations

    28

    h-index

  2. SL
    Stuart L. Schreiber

    Harvard University, United States

    30 publications · 4.5K citations

    25

    h-index

  3. AD
    Alexander Dömlingꝉ

    University of Groningen, Netherlands

    38 publications · 5.8K citations

    24

    h-index

  4. RA
    Richard A. Houghten

    Torrey Pines Institute For Molecular Studies, United States

    27 publications · 2.6K citations

    22

    h-index

  5. DR
    David R. Spring

    University of Cambridge, United Kingdom

    23 publications · 2.1K citations

    21

    h-index

1–5 of 13.1K

Institutions

2.1K

  1. Scripps Research Institute

    San Diego, United States

    54 h-index

    404 publications

    83.5K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    42 h-index

    334 publications

    32.8K citations

  3. Harvard University

    Cambridge, United States

    38 h-index

    180 publications

    20.3K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    37 h-index

    126 publications

    22.6K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    36 h-index

    387 publications

    15.7K citations

  6. Chinese Academy of Sciences

    Beijing, China

    29 h-index

    221 publications

    7.5K citations

  7. University of Pittsburgh

    Pittsburgh, United States

    28 h-index

    177 publications

    8.3K citations

  8. University of Kansas

    Lawrence, United States

    26 h-index

    228 publications

    6.8K citations

1–8 of 2.1K

Venues

  1. Journal of the American Chemical Society

    JACS · 141 publications · 14.9K citations

    76

    h-index

  2. Angewandte Chemie International Edition

    138 publications · 39.5K citations

    70

    h-index

  3. Organic Letters

    OL · 255 publications · 11.4K citations

    59

    h-index

  4. The Journal of Organic Chemistry

    JOC · 200 publications · 9.2K citations

    53

    h-index

  5. Journal of Combinatorial Chemistry

    303 publications · 10.8K citations

    53

    h-index

1–5