David R. Spring

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

Warren R. J. D. Galloway, Albert Isidro‐Llobet, David R. Spring · Nature Communications · 2010 · 854 citations · Full text

Combinatorial Chemistry, Diversity Oriented Synthesis, Molecular Diversity +11

Zn²⁺-Triggered Amide Tautomerization Produces a Highly Zn²⁺-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor

Zhaochao Xu, Kyung-Hwa Baek, Hana Kim et al. · Journal of the American Chemical Society · 2009 · 691 citations

Diversity-oriented synthesis; a challenge for synthetic chemistsElectronic supplementary information (ESI) available: Excel file of all the FDA new molecular entities between the years 1998 and July 2003, and new drug approvals between the years 1990 and 2002. See http://www.rsc.org/suppdata/ob/b3/b310752n/

David R. Spring · Organic & Biomolecular Chemistry · 2003 · 335 citations

Combinatorial Chemistry, Excel File, Bioorganic Chemistry +21

A Lysosome-Targetable Fluorescent Probe for Imaging Hydrogen Sulfide in Living Cells

Tianyu Liu, Zhaochao Xu, David R. Spring et al. · Organic Letters · 2013 · 286 citations

1,8-Naphthalimide-derived Fluorescent Probe, Imaging Hydrogen Sulfide, Molecular Biology +18

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

Jing Huang, Heng Zhu, Stephen J. Haggarty et al. · Proceedings of the National Academy of Sciences · 2004 · 245 citations · Full text