Transgenic Mice Overexpressing APP and Transforming Growth Factor-β1 Feature Cognitive and Vascular Hallmarks of Alzheimer's Disease

High-Level Neuronal Expression of Aβ_1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models

Albert Y. Hsia, Eliezer Masliah, Lisa McConlogue et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Aggregation of vascular risk factors and risk of incident Alzheimer disease

José A. Luchsinger, Christiane Reitz, Lawrence S. Honig et al. · Neurology · 2005 · 786 citations · Full text

Medicine, Geriatric Medicine, Neurology +10

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease.

Alex E. Roher, Jonathan D. Lowenson, Steven Clarke et al. · Proceedings of the National Academy of Sciences · 1993 · 742 citations

Life Sciences, Neurobiology, Neuroscience +17

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating <i>BACE1</i> gene expression

Xiulian Sun, Guiqiong He, Hong Qing et al. · Proceedings of the National Academy of Sciences · 2006 · 601 citations

Life Sciences, Neurology, Neuroscience +17