Jonathan D. Lowenson

Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.

Alex E. Roher, Jonathan D. Lowenson, Steven Clarke et al. · Journal of Biological Chemistry · 1993 · 799 citations · Full text

Life Sciences, Neurology, Neuroscience +17

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease.

Alex E. Roher, Jonathan D. Lowenson, Steven Clarke et al. · Proceedings of the National Academy of Sciences · 1993 · 742 citations

Life Sciences, Neurobiology, Neuroscience +17

Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice

Edward Kim, Jonathan D. Lowenson, Duncan C. MacLaren et al. · Proceedings of the National Academy of Sciences · 1997 · 290 citations

Life Sciences, Molecular Biology, Neurobiology +14

Recognition of D-aspartyl residues in polypeptides by the erythrocyte L-isoaspartyl/D-aspartyl protein methyltransferase. Implications for the repair hypothesis.

Jonathan D. Lowenson, Steven Clarke · Journal of Biological Chemistry · 1992 · 139 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Structural elements affecting the recognition of L-isoaspartyl residues by the L-isoaspartyl/D-aspartyl protein methyltransferase. Implications for the repair hypothesis.

Jonathan D. Lowenson, Steven Clarke · Journal of Biological Chemistry · 1991 · 91 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12