Lisa McConlogue

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

Alzheimer-type Neuropathology, Neurodegenerative Diseases, Alzheimer's Disease +12

High-Level Neuronal Expression of Aβ_1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +15

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations

Neurodegenerative Diseases, Alzheimer's Disease, β-Amyloid Precursor Protein +10

Purification and cloning of amyloid precursor protein β-secretase from human brain

Sukanto Sinha, John P. Anderson, Robin Barbour et al. · Nature · 1999 · 1.6K citations

Neurodegenerative Diseases, Protein Secretion, Molecular Neuroscience +8

Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models

Albert Y. Hsia, Eliezer Masliah, Lisa McConlogue et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations · Full text

Synaptic Transmission, Neurochemical Biomarkers, Amyloid Beta Peptide +16