Concepedia

In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice

Nico Scheer, Jillian Ross, Yury Kapelyukh, Anja Rode, C. Roland Wolf

Drug Metabolism and Disposition · 2010 · 47 citations · 35 references

DOI

Concepts

References

35

Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands

Linda B. Moore, Derek J. Parks, Stacey A. Jones et al. · Journal of Biological Chemistry · 2000 · 810 citations · Full text

, , +17

The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the <i>CYP2B</i> Gene

Paavo Honkakoski, Igor N. Zelko, Tatsuya Sueyoshi et al. · Molecular and Cellular Biology · 1998 · 705 citations

, , +17

Humanized xenobiotic response in mice expressing nuclear receptor SXR

Wen Xie, Joyce L. Barwick, Michael Downes et al. · Nature · 2000 · 657 citations

, , +12

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

Ping Wei, Jun Zhang, Margarete Egan-Hafley et al. · Nature · 2000 · 649 citations

, , +13

Reciprocal activation of Xenobiotic response genes by nuclear receptors SXR/PXR and CAR

Wen Xie, Joyce L. Barwick, Cynthia M. Simon et al. · Genes & Development · 2000 · 508 citations · Full text

, , +14